Assistant Professor, Pediatrics School of Medicine
Awards & Honors
Award
Conferred By
Date
Young Physician-Scientist Award
American Society for Clinical Investigation
2023
Invited speaker
Gordon Conference on Angiogenesis
2023
New Innovator Award (DP2)
NIH NIMH
2023
Leon Levy Neuroscience Awardee
Rockefeller University
2023
Discussion leader
International Vascular Biology Meeting
2022
Bhatt Ramanathan Scholarship Award for excellence in neonatology research
California Association of Neonatologists
2020
Physician Scientists Scholars Program
UCSF
2020
Education
Institution
Degree
Dept or School
End Date
Columbia University
MD
Medicine
Columbia University
PhD
Neuroscience
DePauw University
BA
Biochemistry
University of California, San Francisco
Fellowship
Neonatology
University of California, San Francisco
Residency
Pediatrics
Grants and Funding
Correcting Latent Mechanisms that Underlie Neurodevelopmental Disorders Associated with Congenital Heart Disease | American Heart Association/Additional Ventures | 2024-07-01 - 2027-06-30 | Role: Co-Investigator
A vascular strategy to ameliorate germinal matrix hemorrhage in preterm infants | Burroughs Wellcome Fund | 2023-06-01 - 2027-05-31 | Role: PI
Vascular mural cells in the development of the blood brain barrier | NIH | 2023-09-01 - 2026-08-31 | Role: Principal Investigator
Harnessing vascular stem cells to grow and protect the human brain | California Institute for Regenerative Medicine | 2023-07-01 - 2026-05-31 | Role: PI
Mural stem cells in normal development and germinal matrix hemorrhage in the preterm human brain | NIH | 2020-12-01 - 2025-11-30 | Role: Principal Investigator
New modalities to interrogate the human brain neurovacular unit | University of California Physician Scientist Scholar Program | 2020-07-01 - 2025-06-30 | Role: PI
Mural cells in normal development and germinal matrix hemorrhage in the preterm human brain | American Heart Association Career Development Award | 2021-07-01 - 2024-06-30 | Role: PI
Stage-specific vulnerability of vascular stem cells in preterm brain hemorrhage | California Institute for Regenerative Medicine | 2021-07-01 - 2023-06-30 | Role: PI
Immune cell and vascular interactions in the human blood brain barrier | Hellman Family Clinical-Translational Research Development Award | 2020-07-01 - 2021-06-30 | Role: PI
Vascular development in the human brain | NICHD Pediatric Scientist Development Program (PSDP) | 2018-07-01 - 2020-06-30 | Role:
Publications
MOST RECENT PUBLICATIONS FROM A TOTAL OF 31
The molecular landscape of vascular cells in the human brain.
Perivascular NOTCH3+ Stem Cells Drive Meningioma Tumorigenesis and Resistance to Radiotherapy.
Choudhury A, Cady MA, Lucas CG, Najem H, Phillips JJ, Palikuqi B, Zakimi N, Joseph T, Birrueta JO, Chen WC, Oberheim Bush NA, Hervey-Jumper SL, Klein OD, Toedebusch CM, Horbinski CM, Magill ST, Bhaduri A, Perry A, Dickinson PJ, Heimberger AB, Ashworth A, Crouch EE, Raleigh DR| | PubMed
Proinflammatory immune cells disrupt angiogenesis and promote germinal matrix hemorrhage in prenatal human brain.
Chen J, Crouch EE, Zawadzki ME, Jacobs KA, Mayo LN, Choi JJ, Lin PY, Shaikh S, Tsui J, Gonzalez-Granero S, Waller S, Kelekar A, Kang G, Valenzuela EJ, Birrueta JO, Diafos LN, Wedderburn-Pugh K, Di Marco B, Xia W, Han CZ, Coufal NG, Glass CK, Fancy SPJ, Alfonso J, Kriegstein AR, Oldham MC, Garcia-Verdugo JM, Kutys ML, Lehtinen MK, Combes AJ, Huang EJ| | PubMed
Meningeal solitary fibrous tumor cell states phenocopy cerebral vascular development and homeostasis.
Mirchia K, Choudhury A, Joseph T, Birrueta JO, Phillips JJ, Bhaduri A, Crouch EE, Perry A, Raleigh DR| | PubMed
Glioblastoma Neurovascular Progenitor Orchestrates Tumor Cell Type Diversity.
Fazzari E, Azizad DJ, Yu K, Ge W, Li MX, Nano PR, Kan RL, Tum HA, Tse C, Bayley NA, Haka V, Cadet D, Perryman T, Soto JA, Wick B, Raleigh DR, Crouch EE, Patel KS, Liau LM, Deneen B, Nathanson DA, Bhaduri A| | PubMed
Should neonatal-perinatal medicine move to two-year fellowships?
Shah S, Myers P, Enciso JM, Davis AS, Crouch EE, Scheurer AM, Song C, Lakshminrusimha S| | PubMed
A Vascular-Centric Approach to Autism Spectrum Disorders.
Profiling human brain vascular cells using single-cell transcriptomics and organoids.
Crouch EE, Diafos LN, Valenzuela EJ, Wedderburn-Pugh K, Birrueta JO, Caston J, Joseph T, Andrews MG, Bhaduri A, Huang EJ| | PubMed
Parents' Views on Autopsy, Organ Donation, and Research Donation After Neonatal Death.
Crouch EE, Damas C, Bartrug WC, Shamiyeh A, Scelfo M, Dreyfus M, Gano D, Segal S, Franck LS| | PubMed
LIF signaling regulates outer radial glial to interneuron fate during human cortical development.
Andrews MG, Siebert C, Wang L, White ML, Ross J, Morales R, Donnay M, Bamfonga G, Mukhtar T, McKinney AA, Gemenes K, Wang S, Bi Q, Crouch EE, Parikshak N, Panagiotakos G, Huang E, Bhaduri A, Kriegstein AR| | PubMed
Meningeal solitary fibrous tumor cell states phenocopy cerebral vascular development and homeostasis.
Raleigh D, Mirchia K, Choudhury A, Joseph T, Birrueta J, Phillips J, Bhaduri A, Crouch E, Perry A| | PubMed
NOTCH3 drives meningioma tumorigenesis and resistance to radiotherapy.
Choudhury A, Cady MA, Lucas CG, Najem H, Phillips JJ, Palikuqi B, Zakimi N, Joseph T, Birrueta JO, Chen WC, Bush NAO, Hervey-Jumper SL, Klein OD, Toedebusch CM, Horbinski CM, Magill ST, Bhaduri A, Perry A, Dickinson PJ, Heimberger AB, Ashworth A, Crouch EE, Raleigh DR| | PubMed
Disentangling brain vasculature in neurogenesis and neurodegeneration using single-cell transcriptomics.
A Case of Neonatal Lupus Presenting with Myocardial Dysfunction in the Absence of Congenital Heart Block (CHB): Clinical Management and Brief Literature Review of Neonatal Cardiac Lupus.
Jain S, Spadafora R, Maxwell S, Botas C, Nawaytou H, von Scheven E, Crouch EE| | PubMed
Ensembles of endothelial and mural cells promote angiogenesis in prenatal human brain.
Crouch EE, Bhaduri A, Andrews MG, Cebrian-Silla A, Diafos LN, Birrueta JO, Wedderburn-Pugh K, Valenzuela EJ, Bennett NK, Eze UC, Sandoval-Espinosa C, Chen J, Mora C, Ross JM, Howard CE, Gonzalez-Granero S, Lozano JF, Vento M, Haeussler M, Paredes MF, Nakamura K, Garcia-Verdugo JM, Alvarez-Buylla A, Kriegstein AR, Huang EJ| | PubMed
Developmental dynamics of RNA translation in the human brain.
Duffy EE, Finander B, Choi G, Carter AC, Pritisanac I, Alam A, Luria V, Karger A, Phu W, Sherman MA, Assad EG, Pajarillo N, Khitun A, Crouch EE, Ganesh S, Chen J, Berger B, Sestan N, O'Donnell-Luria A, Huang EJ, Griffith EC, Forman-Kay JD, Moses AM, Kalish BT, Greenberg ME| | PubMed
Tropism of SARS-CoV-2 for human cortical astrocytes.
Andrews MG, Mukhtar T, Eze UC, Simoneau CR, Ross J, Parikshak N, Wang S, Zhou L, Koontz M, Velmeshev D, Siebert CV, Gemenes KM, Tabata T, Perez Y, Wang L, Mostajo-Radji MA, de Majo M, Donohue KC, Shin D, Salma J, Pollen AA, Nowakowski TJ, Ullian E, Kumar GR, Winkler EA, Crouch EE, Ott M, Kriegstein AR| | PubMed
Individual human cortical progenitors can produce excitatory and inhibitory neurons.
Delgado RN, Allen DE, Keefe MG, Mancia Leon WR, Ziffra RS, Crouch EE, Alvarez-Buylla A, Nowakowski TJ| | PubMed
The Expanding Cell Diversity of the Brain Vasculature.
Ross JM, Kim C, Allen D, Crouch EE, Narsinh K, Cooke DL, Abla AA, Nowakowski TJ, Winkler EA| | PubMed
Reciprocal Interaction between Vascular Filopodia and Neural Stem Cells Shapes Neurogenesis in the Ventral Telencephalon.
Di Marco B, Crouch EE, Shah B, Duman C, Paredes MF, Ruiz de Almodovar C, Huang EJ, Alfonso J| | PubMed
Human organoids to model the developing human neocortex in health and disease.
