University of California San Francisco

elizabeth.crouch
Elizabeth Crouch, MD, PhD

Assistant Professor, Pediatrics
School of Medicine

Education

Institution Degree Dept or School End Date
Columbia University MD Medicine
Columbia University PhD Neuroscience
DePauw University BA Biochemistry
University of California, San Francisco Fellowship Neonatology
University of California, San Francisco Residency Pediatrics

Awards & Honors

Award Conferred By Date
Young Physician-Scientist Award American Society for Clinical Investigation 2023
Invited speaker Gordon Conference on Angiogenesis 2023
New Innovator Award (DP2) NIH NIMH 2023
Leon Levy Neuroscience Awardee Rockefeller University 2023
Discussion leader International Vascular Biology Meeting 2022
Bhatt Ramanathan Scholarship Award for excellence in neonatology research California Association of Neonatologists 2020
Physician Scientists Scholars Program UCSF 2020

Grants and Funding

  • Correcting Latent Mechanisms that Underlie Neurodevelopmental Disorders Associated with Congenital Heart Disease | American Heart Association/Additional Ventures | 2024-07-01 - 2027-06-30 | Role: Co-Investigator
  • A vascular strategy to ameliorate germinal matrix hemorrhage in preterm infants | Burroughs Wellcome Fund | 2023-06-01 - 2027-05-31 | Role: PI
  • Vascular mural cells in the development of the blood brain barrier | NIH | 2023-09-01 - 2026-08-31 | Role: Principal Investigator
  • Harnessing vascular stem cells to grow and protect the human brain | California Institute for Regenerative Medicine | 2023-07-01 - 2026-05-31 | Role: PI
  • Mural stem cells in normal development and germinal matrix hemorrhage in the preterm human brain | NIH | 2020-12-01 - 2025-11-30 | Role: Principal Investigator
  • New modalities to interrogate the human brain neurovacular unit | University of California Physician Scientist Scholar Program | 2020-07-01 - 2025-06-30 | Role: PI
  • Mural cells in normal development and germinal matrix hemorrhage in the preterm human brain | American Heart Association Career Development Award | 2021-07-01 - 2024-06-30 | Role: PI
  • Stage-specific vulnerability of vascular stem cells in preterm brain hemorrhage | California Institute for Regenerative Medicine | 2021-07-01 - 2023-06-30 | Role: PI
  • Immune cell and vascular interactions in the human blood brain barrier | Hellman Family Clinical-Translational Research Development Award | 2020-07-01 - 2021-06-30 | Role: PI
  • Vascular development in the human brain | NICHD Pediatric Scientist Development Program (PSDP) | 2018-07-01 - 2020-06-30 | Role:

Publications

MOST RECENT PUBLICATIONS FROM A TOTAL OF 33
  1. Parents' Views on Autopsy, Organ Donation, and Research Donation After Neonatal Death.
    Crouch EE, Damas C, Bartrug WC, Shamiyeh A, Scelfo M, Dreyfus M, Gano D, Segal S, Franck LS| | PubMed
  2. LIF signaling regulates outer radial glial to interneuron fate during human cortical development.
    Andrews MG, Siebert C, Wang L, White ML, Ross J, Morales R, Donnay M, Bamfonga G, Mukhtar T, McKinney AA, Gemenes K, Wang S, Bi Q, Crouch EE, Parikshak N, Panagiotakos G, Huang E, Bhaduri A, Kriegstein AR| | PubMed
  3. Meningeal solitary fibrous tumor cell states phenocopy cerebral vascular development and homeostasis.
    Raleigh D, Mirchia K, Choudhury A, Joseph T, Birrueta J, Phillips J, Bhaduri A, Crouch E, Perry A| | PubMed
  4. NOTCH3 drives meningioma tumorigenesis and resistance to radiotherapy.
    Choudhury A, Cady MA, Lucas CG, Najem H, Phillips JJ, Palikuqi B, Zakimi N, Joseph T, Birrueta JO, Chen WC, Bush NAO, Hervey-Jumper SL, Klein OD, Toedebusch CM, Horbinski CM, Magill ST, Bhaduri A, Perry A, Dickinson PJ, Heimberger AB, Ashworth A, Crouch EE, Raleigh DR| | PubMed
  5. Disentangling brain vasculature in neurogenesis and neurodegeneration using single-cell transcriptomics.
    Crouch EE, Joseph T, Marsan E, Huang EJ| | PubMed
  6. A Case of Neonatal Lupus Presenting with Myocardial Dysfunction in the Absence of Congenital Heart Block (CHB): Clinical Management and Brief Literature Review of Neonatal Cardiac Lupus.
    Jain S, Spadafora R, Maxwell S, Botas C, Nawaytou H, von Scheven E, Crouch EE| | PubMed
  7. Ensembles of endothelial and mural cells promote angiogenesis in prenatal human brain.
    Crouch EE, Bhaduri A, Andrews MG, Cebrian-Silla A, Diafos LN, Birrueta JO, Wedderburn-Pugh K, Valenzuela EJ, Bennett NK, Eze UC, Sandoval-Espinosa C, Chen J, Mora C, Ross JM, Howard CE, Gonzalez-Granero S, Lozano JF, Vento M, Haeussler M, Paredes MF, Nakamura K, Garcia-Verdugo JM, Alvarez-Buylla A, Kriegstein AR, Huang EJ| | PubMed
  8. Developmental dynamics of RNA translation in the human brain.
    Duffy EE, Finander B, Choi G, Carter AC, Pritisanac I, Alam A, Luria V, Karger A, Phu W, Sherman MA, Assad EG, Pajarillo N, Khitun A, Crouch EE, Ganesh S, Chen J, Berger B, Sestan N, O'Donnell-Luria A, Huang EJ, Griffith EC, Forman-Kay JD, Moses AM, Kalish BT, Greenberg ME| | PubMed
  9. Tropism of SARS-CoV-2 for human cortical astrocytes.
    Andrews MG, Mukhtar T, Eze UC, Simoneau CR, Ross J, Parikshak N, Wang S, Zhou L, Koontz M, Velmeshev D, Siebert CV, Gemenes KM, Tabata T, Perez Y, Wang L, Mostajo-Radji MA, de Majo M, Donohue KC, Shin D, Salma J, Pollen AA, Nowakowski TJ, Ullian E, Kumar GR, Winkler EA, Crouch EE, Ott M, Kriegstein AR| | PubMed
  10. Individual human cortical progenitors can produce excitatory and inhibitory neurons.
    Delgado RN, Allen DE, Keefe MG, Mancia Leon WR, Ziffra RS, Crouch EE, Alvarez-Buylla A, Nowakowski TJ| | PubMed
33
View all 33 Publications
MOST RECENT PUBLICATIONS FROM A TOTAL OF 33
  1. NICU Voices: Understanding Parent Perspectives of Research in the Neonatal Intensive Care Unit.
    Coloma M, Nguyen B, Bartrug WC, Swander LM, Silva KL, Villegas E, Numis A, McQuillen P, Peyvandi S, Rogers EE, Crouch EE, Paredes M| | PubMed
  2. The promise of cerebral organoids for neonatology.
    Howard CE, Cheenath M, Crouch EE| | PubMed
  3. Meningeal solitary fibrous tumor cell states phenocopy cerebral vascular development and homeostasis.
    Mirchia K, Choudhury A, Joseph T, Birrueta JO, Phillips JJ, Bhaduri A, Crouch EE, Perry A, Raleigh DR| | PubMed
  4. The molecular landscape of vascular cells in the human brain.
    Crouch EE| | PubMed
  5. Perivascular NOTCH3+ Stem Cells Drive Meningioma Tumorigenesis and Resistance to Radiotherapy.
    Choudhury A, Cady MA, Lucas CG, Najem H, Phillips JJ, Palikuqi B, Zakimi N, Joseph T, Birrueta JO, Chen WC, Oberheim Bush NA, Hervey-Jumper SL, Klein OD, Toedebusch CM, Horbinski CM, Magill ST, Bhaduri A, Perry A, Dickinson PJ, Heimberger AB, Ashworth A, Crouch EE, Raleigh DR| | PubMed
  6. Proinflammatory immune cells disrupt angiogenesis and promote germinal matrix hemorrhage in prenatal human brain.
    Chen J, Crouch EE, Zawadzki ME, Jacobs KA, Mayo LN, Choi JJ, Lin PY, Shaikh S, Tsui J, Gonzalez-Granero S, Waller S, Kelekar A, Kang G, Valenzuela EJ, Birrueta JO, Diafos LN, Wedderburn-Pugh K, Di Marco B, Xia W, Han CZ, Coufal NG, Glass CK, Fancy SPJ, Alfonso J, Kriegstein AR, Oldham MC, Garcia-Verdugo JM, Kutys ML, Lehtinen MK, Combes AJ, Huang EJ| | PubMed
  7. Glioblastoma Neurovascular Progenitor Orchestrates Tumor Cell Type Diversity.
    Fazzari E, Azizad DJ, Yu K, Ge W, Li MX, Nano PR, Kan RL, Tum HA, Tse C, Bayley NA, Haka V, Cadet D, Perryman T, Soto JA, Wick B, Raleigh DR, Crouch EE, Patel KS, Liau LM, Deneen B, Nathanson DA, Bhaduri A| | PubMed
  8. Should neonatal-perinatal medicine move to two-year fellowships?
    Shah S, Myers P, Enciso JM, Davis AS, Crouch EE, Scheurer AM, Song C, Lakshminrusimha S| | PubMed
  9. A Vascular-Centric Approach to Autism Spectrum Disorders.
    Ouellette J, Crouch EE, Morel JL, Coelho-Santos V, Lacoste B| | PubMed
  10. Profiling human brain vascular cells using single-cell transcriptomics and organoids.
    Crouch EE, Diafos LN, Valenzuela EJ, Wedderburn-Pugh K, Birrueta JO, Caston J, Joseph T, Andrews MG, Bhaduri A, Huang EJ| | PubMed
  11. Parents' Views on Autopsy, Organ Donation, and Research Donation After Neonatal Death.
    Crouch EE, Damas C, Bartrug WC, Shamiyeh A, Scelfo M, Dreyfus M, Gano D, Segal S, Franck LS| | PubMed
  12. LIF signaling regulates outer radial glial to interneuron fate during human cortical development.
    Andrews MG, Siebert C, Wang L, White ML, Ross J, Morales R, Donnay M, Bamfonga G, Mukhtar T, McKinney AA, Gemenes K, Wang S, Bi Q, Crouch EE, Parikshak N, Panagiotakos G, Huang E, Bhaduri A, Kriegstein AR| | PubMed
  13. Meningeal solitary fibrous tumor cell states phenocopy cerebral vascular development and homeostasis.
    Raleigh D, Mirchia K, Choudhury A, Joseph T, Birrueta J, Phillips J, Bhaduri A, Crouch E, Perry A| | PubMed
  14. NOTCH3 drives meningioma tumorigenesis and resistance to radiotherapy.
    Choudhury A, Cady MA, Lucas CG, Najem H, Phillips JJ, Palikuqi B, Zakimi N, Joseph T, Birrueta JO, Chen WC, Bush NAO, Hervey-Jumper SL, Klein OD, Toedebusch CM, Horbinski CM, Magill ST, Bhaduri A, Perry A, Dickinson PJ, Heimberger AB, Ashworth A, Crouch EE, Raleigh DR| | PubMed
  15. Disentangling brain vasculature in neurogenesis and neurodegeneration using single-cell transcriptomics.
    Crouch EE, Joseph T, Marsan E, Huang EJ| | PubMed
  16. A Case of Neonatal Lupus Presenting with Myocardial Dysfunction in the Absence of Congenital Heart Block (CHB): Clinical Management and Brief Literature Review of Neonatal Cardiac Lupus.
    Jain S, Spadafora R, Maxwell S, Botas C, Nawaytou H, von Scheven E, Crouch EE| | PubMed
  17. Ensembles of endothelial and mural cells promote angiogenesis in prenatal human brain.
    Crouch EE, Bhaduri A, Andrews MG, Cebrian-Silla A, Diafos LN, Birrueta JO, Wedderburn-Pugh K, Valenzuela EJ, Bennett NK, Eze UC, Sandoval-Espinosa C, Chen J, Mora C, Ross JM, Howard CE, Gonzalez-Granero S, Lozano JF, Vento M, Haeussler M, Paredes MF, Nakamura K, Garcia-Verdugo JM, Alvarez-Buylla A, Kriegstein AR, Huang EJ| | PubMed
  18. Developmental dynamics of RNA translation in the human brain.
    Duffy EE, Finander B, Choi G, Carter AC, Pritisanac I, Alam A, Luria V, Karger A, Phu W, Sherman MA, Assad EG, Pajarillo N, Khitun A, Crouch EE, Ganesh S, Chen J, Berger B, Sestan N, O'Donnell-Luria A, Huang EJ, Griffith EC, Forman-Kay JD, Moses AM, Kalish BT, Greenberg ME| | PubMed
  19. Tropism of SARS-CoV-2 for human cortical astrocytes.
    Andrews MG, Mukhtar T, Eze UC, Simoneau CR, Ross J, Parikshak N, Wang S, Zhou L, Koontz M, Velmeshev D, Siebert CV, Gemenes KM, Tabata T, Perez Y, Wang L, Mostajo-Radji MA, de Majo M, Donohue KC, Shin D, Salma J, Pollen AA, Nowakowski TJ, Ullian E, Kumar GR, Winkler EA, Crouch EE, Ott M, Kriegstein AR| | PubMed
  20. Individual human cortical progenitors can produce excitatory and inhibitory neurons.
    Delgado RN, Allen DE, Keefe MG, Mancia Leon WR, Ziffra RS, Crouch EE, Alvarez-Buylla A, Nowakowski TJ| | PubMed
  21. The Expanding Cell Diversity of the Brain Vasculature.
    Ross JM, Kim C, Allen D, Crouch EE, Narsinh K, Cooke DL, Abla AA, Nowakowski TJ, Winkler EA| | PubMed
  22. Reciprocal Interaction between Vascular Filopodia and Neural Stem Cells Shapes Neurogenesis in the Ventral Telencephalon.
    Di Marco B, Crouch EE, Shah B, Duman C, Paredes MF, Ruiz de Almodovar C, Huang EJ, Alfonso J| | PubMed
  23. Human organoids to model the developing human neocortex in health and disease.
    Khakipoor S, Crouch EE, Mayer S| | PubMed
  24. Outer Radial Glia-like Cancer Stem Cells Contribute to Heterogeneity of Glioblastoma.
    Bhaduri A, Di Lullo E, Jung D, Müller S, Crouch EE, Espinosa CS, Ozawa T, Alvarado B, Spatazza J, Cadwell CR, Wilkins G, Velmeshev D, Liu SJ, Malatesta M, Andrews MG, Mostajo-Radji MA, Huang EJ, Nowakowski TJ, Lim DA, Diaz A, Raleigh DR, Kriegstein AR| | PubMed
  25. Prevalence of adverse childhood experiences (ACEs) among US children.
    Crouch E, Probst JC, Radcliff E, Bennett KJ, McKinney SH| | PubMed
  26. FACS isolation of endothelial cells and pericytes from mouse brain microregions.
    Crouch EE, Doetsch F| | PubMed
  27. Examining the association between adverse childhood experiences and smoking-exacerbated illnesses.
    Crouch E, Radcliff E, Strompolis M, Wilson A| | PubMed
  28. Regional and stage-specific effects of prospectively purified vascular cells on the adult V-SVZ neural stem cell lineage.
    Crouch EE, Liu C, Silva-Vargas V, Doetsch F| | PubMed
  29. Novel association of early onset hepatocellular carcinoma with transaldolase deficiency.
    Leduc CA, Crouch EE, Wilson A, Lefkowitch J, Wamelink MM, Jakobs C, Salomons GS, Sun X, Shen Y, Chung WK| | PubMed
  30. Adult neural stem cells and their niche: a dynamic duo during homeostasis, regeneration, and aging.
    Silva-Vargas V, Crouch EE, Doetsch F| | PubMed
  31. The ATM repair pathway inhibits RNA polymerase I transcription in response to chromosome breaks.
    Kruhlak M, Crouch EE, Orlov M, Montaño C, Gorski SA, Nussenzweig A, Misteli T, Phair RD, Casellas R| | PubMed
  32. Regulation of AID expression in the immune response.
    Crouch EE, Li Z, Takizawa M, Fichtner-Feigl S, Gourzi P, Montaño C, Feigenbaum L, Wilson P, Janz S, Papavasiliou FN, Casellas R| | PubMed
  33. Interactions of recombinant human pulmonary surfactant protein D and SP-D multimers with influenza A.
    Hartshorn K, Chang D, Rust K, White M, Heuser J, Crouch E| | PubMed