University of California San Francisco

Matthew Spitzer, PhD

Matthew Spitzer, PhD
Matthew Spitzer, PhD

Associate Professor, Otolaryngology
School of Medicine

Address

513 Parnassus Avenue, HSW, #1501A
San Francisco, CA 94143
United States

Email: [email protected]

ORCID: 0000-0002-5291-3819

Education

Institution Degree Dept or School End Date
Georgetown University BS Biology
Stanford University PhD Immunology

Grants and Funding

  • Early identification of immunotherapy resistance through integrated multiparameter imaging | NIH | 2025-01-01 - 2029-12-31 | Role: Co-Principal Investigator
  • Immune determinants of progression from Oral Epithelial Dysplasia to Oral Squamous Cell Carcinoma by precision multiplexed imaging | NIH | 2022-06-15 - 2027-03-31 | Role: Principal Investigator
  • Quantitatively modeling immune responses to cancer | NIH | 2016-09-21 - 2021-08-31 | Role: Principal Investigator
  • Single-cell High-dimensional Characterization of the Bone Marrow Microenvironment in Health and Disease | NIH | 2017-07-15 - 2019-05-31 | Role: Co-Principal Investigator
  • Revealing the tumor-immune network by mass cytometry | NIH | 2014-09-30 - 2018-09-29 | Role: Principal Investigator

Publications

MOST RECENT PUBLICATIONS FROM A TOTAL OF 10
  1. IL6 Supports Development of an Immunosuppressive Microenvironment and Resistance to Therapy in Glioblastoma.
    Young JS, Cho NW, Lucas CG, Najem H, Mirchia K, Chen WC, Tamaki C, Congivaram H, Seo K, Zakimi N, Daggubati V, Casey-Clyde T, Nguyen MP, Chen Z, Phillips JJ, Ozawa T, Aghi MK, Taylor JW, DeRisi JL, Bhaduri A, Berger MS, Heimberger AB, Butowski NA, Spitzer MH, Raleigh DR| | PubMed
  2. ATF7ip Inhibits the Tumor Immune Response by Promoting Terminal CD8+ T-cell Exhaustion.
    Kashyap S, Sin JH, Guldberg SM, Yee JL, Lopez-Ichikawa M, Phillips SH, Spitzer MH, Waterfield M| | PubMed
  3. Immune activation during broadly neutralizing antibody-mediated HIV suppression prior to post-intervention control.
    Wagner JA, Sandel DA, Patel RK, Gruenhagen GW, Tibúrcio R, Singh SS, Schwartz K, Traglia M, Milani P, Di Germanio C, Ilan S, Dalhuisen T, Hoh R, Williams MC, Shimoda M, Thomas R, Juelg B, Spitzer MH, Deitchman AN, Busch MP, Fragiadakis GK, Hunt PW, Peluso MJ, Deeks SG, Rutishauser RL| | PubMed
  4. Scalable longitudinal imaging and transcriptomics of cells in dynamic enclosures.
    Khurana TK, Wu LY, Gherardini PF, Moeinzadeh S, Mohseni M, Yasar FG, Dettloff R, Poelma J, Sabri S, Scaramozza A, Li Y, Rouzbeh N, Elder N, Deshmukh S, Majd A, Gupta R, Farahvashi S, Thomas I, Betts C, Charbonier F, Roberts D, Hsiung PL, Zargari-Pariset E, Yau R, Vila OF, Phillips M, Xiao C, Wang J, Zhou Y, Adhikari P, Taing M, Farjami E, Javanmardi B, Siu M, Cellanome Development Team, Valente C, Cox C, Geiger-Schuller K, Turley SJ, Rozenblatt-Rosen O, Fattahi F, Ecker JR, Jones JR, Gage FH, Spitzer MH, Pritchard J, Kupershmidt I, Lundberg P, Levy S, Ostadan O, Schroth GP, Ronaghi M| | PubMed
  5. Reprogramming T cell-myeloid crosstalk overcomes immune resistance in colorectal cancer.
    Mestrallet G, Brown M, Vaninov N, Cho NW, Velazquez L, Ananthanarayanan A, Spitzer M, Vabret N, Cimen Bozkus C, Samstein RM, Bhardwaj N| | PubMed
  6. A widespread gut bacterial lineage distinguished by redox metabolism and phage defense.
    Noecker C, Guo L, Daté C, Rai N, Daramy F, Ramirez Hernandez LA, Kyaw TS, Trepka KR, Gupta CL, Ha CWY, Babdor J, Spitzer MH, Turnbaugh PJ| | PubMed
  7. Immune checkpoints in a genetically engineered mouse model of spontaneous autoimmune uveitis.
    Yin M, Hiam-Galvez KJ, Proekt I, Chan J, Hu Y, Lowell CA, Caspi RR, Spitzer MH, Anderson MS, DeFranco AL| | PubMed
  8. Immune-microbiome coordination defines interferon setpoints in healthy humans.
    Babdor J, Patel RK, Davidson B, Koser K, Noecker C, Rahim MK, Bisanz JE, Tenvooren I, Marquez D, Calvo M, Johri V, McCarthy EE, Shaheed A, Ekstrand C, Weakley AM, Yu FB, Krip K, Shaikh KA, Amatullah H, Fiehn O, Turnbaugh PJ, Combes AJ, Fragiadakis GK, Spitzer MH| | PubMed
  9. Phase II Study of Pembrolizumab Plus Capecitabine and Bevacizumab for Microsatellite Stable/Mismatch Repair-Proficient Metastatic Colorectal Cancer.
    Bocobo A, Whitman J, Keenan BP, Koser KL, Kidder WA, Piawah S, Van Loon K, Behr SC, Kolli KP, Chen X, Onodera C, Pande M, Pollak M, Wang R, Babdor J, Spitzer MH, Zhang L, Fong L, Atreya CE| | PubMed
  10. Commensal-myeloid crosstalk in neonatal skin regulates interleukin-1 signaling and cutaneous type 17 inflammation.
    Dhariwala MO, Carale RO, DeRogatis AM, Rodriguez-Valbuena H, Okoro JN, Ekstrand CA, Weckel A, Tran VM, Habrylo I, Barrere-Cain R, Ojewumi OT, Tammen AE, Tsui J, Shaikh S, Yellamilli S, Aladhami AK, Schwartz R, Leech JM, Merana GR, Hiam-Galvez KJ, Mack M, Halkias J, Gardner JM, Rutishauser RL, Fragiadakis GK, Spitzer MH, Combes AJ, Scharschmidt TC| | PubMed